Leukocyte Cpd by in the Detection of Sarscov- 2 Pneumonia

Introduction: Leukocyte differential, present certain features in SARS-CoV2 infected patients neutrophilia, lymphopenia and morphology alterations, which could be useful for screening. Cell population data (CPD) are reported as part of leukocyte differentials by Sysmex XN analyze;they are morphometric parameters that characterize neutrophils, lymphocytes and monocytes and classify them according to their volume, granularity and their content in nucleic acids. CPD reflects in numbers the changes in morphology and activation status triggered by infections. We aimed to evaluate the predictive power of CPDs for the differential diagnosis of COVID19 versus non-COVID19 pneumonia. Method(s): The prospective, observational, multicenter study was conducted in 3 hospitals, including patients > 18 years admitted with the diagnosis community-acquired pneumonia in the period November 2019 - October 2020. Complete blood count were analyzed using Sysmex XN counters. Diagnosis of SARS-CoV-2 infection was done using real-time reverse transcriptionpolymerase chain reaction. Patients were divided into two groups: (1) referral cohort in a hospital for the development of the model (2) the sample of two other hospitals for its validation. Multivariate logistic regression model has been developed for the detection of COVID patients. Robustness of the model has been evaluated by means of the area under the ROC curve and the calibration of the model. Statisticalsignificance p < 0.05. Result(s): 598 patients were recruited, 322 in the referral cohort and 276 in the validation group. The average age was 67.0 years (Standard Deviation 14.59 years ) and 61.49 % male. Neutrophil lymphocyte ratio, NE-WZ, LYY, LY-Z, LY-WX, LY- WY, MO- WY, MO-Z were included in the multivariate analysis, and presented a significant association for the differential diagnosis of SARS-CoV-2 infection with AUC of 0.84 (95% CI 0.82-0.92) in the referral cohort and 0.77 (0.69-0.85) in the validation cohort Conclusion(s): Leukocyte differential and CPDs could be very useful in the differential diagnosis of SARS-CoV-2 pneumonia and lead to a cheap and early diagnosis of the disease.

The post-COVID-19 tourism recovery led by crisis-resistant tourists: Surf tourism preferences in the Canary Islands

The post-COVID-19 tourism recovery is most likely to be led by crisis-resistant tourists (Hajibaba, Gretzel, Leisch and Dolnicar, 2015). The surf tourism market is highly crisis resistant (Dolnicar and Fluker, 2003a) and has potential to expand during the pandemic (Mach and Ponting, 2021), especially with the advances in technologies for remote workers. In an attempt to answer Hritz and Franzidis' (2018) call for further research on this niche market in order to ascertain the significance of surf tourism in a particular community, we provide a baseline for surf tourism in terms of these niche preferences and satisfaction levels in Gran Canaria (Spain). The study is based on a discrete choice model that relies on preferences elicited through best-worst scaling methods. Our research demonstrates that the BWS scores can be used to develop a destination attribute quality index based on importance and satisfaction scales and provides important information to destination managers. © 2022 The Authors

Installing oncofertility programs for common cancers in limited resource settings (Repro-Can-OPEN Study): An extrapolation during the global crisis of Coronavirus (COVID-19) pandemic.

PURPOSE: The state of limited resource settings that Coronavirus (COVID-19) pandemic has created globally should be taken seriously into account especially in healthcare sector. In oncofertility, patients should receive their fertility preservation treatments urgently even in limited resource settings before initiation of anticancer therapy. Therefore, it is very crucial to learn more about oncofertility practice in limited resource settings such as in developing countries that suffer often from shortage of healthcare services provided to young patients with cancer. METHODS: As an extrapolation during the global crisis of COVID-19 pandemic, we surveyed oncofertility centers from 14 developing countries (Egypt, Tunisia, Brazil, Peru, Panama, Mexico, Colombia, Guatemala, Argentina, Chile, Nigeria, South Africa, Saudi Arabia, and India). Survey questionnaire included questions on the availability and degree of utilization of fertility preservation options in case of childhood cancer, breast cancer, and blood cancer. RESULTS: All surveyed centers responded to all questions. Responses and their calculated oncofertility scores showed different domestic standards for oncofertility practice in case of childhood cancer, breast cancer, and blood cancer in the developing countries under limited resource settings. CONCLUSIONS: Medical practice in limited resource settings has become a critical topic especially after the global crisis of COVID-19 pandemic. Understanding the resources necessary to provide oncofertility treatments is important until the current COVID-19 pandemic resolves. Lessons learned will be valuable to future potential worldwide disruptions due to infectious diseases or other global crises.